Allele Frequency Net Database logo

The KIR and Diseases Database (KDDB)

The KIR and Diseases Database (KDDB) is also a section of the Allele Frequencies Net Database (AFND). The aim of this module is to provide users with an open source database listing known disease interactions between killer-cell immunoglobulin-like receptors (KIR) variants. Many infectious and autoimmune diseases have been associated with KIR genes in different ways, e.g. associations with single genes (or single alleles) to associations with groups of genes and full genotypes. As KIR disease association studies are in its infancy compared with HLA, we decided to start collecting KIR disease associations, as a new module within AFND.

The success of this module depends on your contribution. Please contact us if you have data to contribute.

Please cite this website using the following reference:

A web resource for mining HLA associations with adverse drug reactions: HLA-ADR Database

Takeshita LY, Gonzalez-Galarza FF, dos Santos EJ, Maia MH, Rahman MM, Zain SM, Middleton D, Jones AR.

Database. 2013 doi: 10.1093/database/bat021

Full text
Database information
Database InformationTotal
Countries50
Disease association records1945
Published studies274